Lyme IgG and IgM Antibody

Lyme IgG and IgM Antibody Tests: Detecting Lyme Disease with Precision

Lyme disease is a tick-borne illness caused by the bacterium Borrelia burgdorferi. It is a multisystem infection that can affect the skin, joints, heart, and nervous system. While the condition is most common in North America and parts of Europe, increasing travel and climate change have contributed to growing global awareness, including in India.

To detect Lyme disease, two main types of antibody tests are used—Lyme IgM and IgG. At Dr. Dangs Lab, one of the best diagnostic labs in Delhi NCR, these tests are conducted using the advanced VIDAS® ELFA method to ensure accurate and timely diagnosis.

What Are Lyme IgM and IgG Tests?

The Lyme IgM and Lyme IgG tests are blood tests that help identify the presence of antibodies against Borrelia burgdorferi. These antibodies develop in response to an infection and can be indicators of early or late stages of Lyme disease.

Lyme IgM Antibody Test

• Purpose: Detects early-stage infection.
• When it appears: Usually within 1–2 weeks of exposure.
• nterpretation:

• Negative: Index < 0.20
• Equivocal: Index ≥ 0.20 to < 0.32
• Positive: Index ≥ 0.32

Lyme IgG Antibody Test

• Purpose: Indicates past or ongoing infection.
• When it appears: Develops 4–6 weeks after infection and can remain for years.
• Interpretation:

• Negative: Index < 0.20
• Positive: Index ≥ 0.20

Why Testing Matters

Lyme disease can present a wide range of symptoms, including:

• Fever and chills
• Headache and fatigue
• Muscle and joint aches
• Rash (often shaped like a bull’s-eye)
• Neurological symptoms in later stages

Without timely treatment, the disease may cause serious health issues. Hence, early diagnosis using reliable lab testing is vital.

How Dr. Dangs Lab Ensures Accuracy

Dr. Dangs Lab follows strict quality protocols and uses advanced VIDAS® ELFA technology (Enzyme-Linked Fluorescent Assay) to test for Lyme antibodies. This method offers:

• High sensitivity and specificity
• Rapid turnaround time
• Automated and standardised procedures
• Result correlation with clinical findings

Their expertise in infectious disease serology, coupled with experienced microbiologists and pathologists, makes Dr. Dangs Lab a trusted name among the best pathology labs in Delhi NCR.

What to Expect During the Test

1. Sample Collection: A small blood sample is taken, usually from a vein in the arm.
2. Home Collection Available: Dr. Dangs Lab provides sample collection from your home for convenience. You can book it via our website or via call.
3. Reporting: Results are shared via email, SMS, or via whatsapp ensuring timely access.
4. vInterpretation: The results are interpreted in combination with symptoms and other diagnostic findings.

What to Expect During the Test

1. Sample Collection: A small blood sample is taken, usually from a vein in the arm.
2. Home Collection Available: Dr. Dangs Lab provides sample collection from your home for convenience. You can book it via our website or via call.
3. Reporting: Results are shared via email, SMS, or via whatsapp ensuring timely access.
4. Interpretation: The results are interpreted in combination with symptoms and other diagnostic findings.

Limitations and Considerations

1. False Positives: Other infections may interfere and cause misleading results.
2. Early Infection: In the early days of exposure, antibody levels may be too low to detect.
3. Second Testing: If symptoms persist, retesting after 4–6 weeks is recommended.
4. Clinical Correlation Essential: Lab results must always be interpreted along with clinical history and symptoms.

FAQs

Q1. What is the difference between Lyme IgM and IgG tests?

IgM detects recent infections (appears early), while IgG indicates long-standing or past infections (appears later and lasts longer).

Q2. Can a person test negative and still have Lyme disease?

Yes, especially in early stages. The immune system may not have produced enough antibodies. In such cases, a second test after 4–6 weeks may help.

Q3. How is the sample collected for Lyme testing?

A blood sample is collected from a vein. At Dr. Dangs Lab, home collection services are available for convenience.

Q4. Is it necessary to take both IgM and IgG tests?

Yes, testing for both helps detect Lyme disease at various stages and gives a more complete picture of the infection.

Q5. Where can I get a Lyme disease test in Delhi NCR?

You can book your test at Dr. Dangs Lab, one of the best diagnostic labs in Delhi NCR, known for its accuracy, technology, and expert guidance.

Final Thoughts

Lyme disease may not be commonly discussed in India, but with increased travel and exposure, awareness is crucial. Early diagnosis and appropriate antibiotic treatment can prevent complications. If you suspect symptoms, especially after a visit to wooded or grassy areas, consult your doctor and get tested without delay. Kindly ensure all antibody-based test results are interpreted in clinical context, as false positives due to cross-reactivity may occur.

Dr. Dangs Lab provides trusted, science-backed testing using globally accepted methods like ELFA, ensuring that your health remains the top priority.

Reliable Source of Information:

1. CDC (Centers for Disease Control and Prevention) guidelines
2. VIDAS® ELFA methodology by bioMérieux